The Connection Between Cinnarizine and Weight Gain

The Connection Between Cinnarizine and Weight Gain
May, 6 2023 Kendrick Wilkerson

Introduction to Cinnarizine and Weight Gain

As a health-conscious individual, I am always on the lookout for information on medications and their potential side effects. One such medication that has caught my attention is Cinnarizine. While it is quite effective in treating a variety of conditions like vertigo, motion sickness, and Meniere's disease, there have been some concerns about its connection to weight gain. In this article, I will explore this connection and help you understand the possible reasons behind it.

Understanding the Mechanism of Cinnarizine

Before we delve into the connection between Cinnarizine and weight gain, let's first understand how this medication works. Cinnarizine is an antihistamine and calcium channel blocker, which means it helps to reduce the effects of histamine in the body. Histamine is a chemical that is responsible for causing inflammation, allergic reactions, and other symptoms. By blocking the action of histamine, Cinnarizine can effectively relieve symptoms associated with the conditions it is used to treat.

Additionally, as a calcium channel blocker, Cinnarizine works by preventing the entry of calcium into cells, which can help to relax blood vessels and improve blood flow. This is particularly beneficial for individuals with Meniere's disease, as it can help to reduce the severity of vertigo episodes.

Potential Causes of Weight Gain in Cinnarizine Users

Now that we have a basic understanding of how Cinnarizine works, let's explore the potential reasons behind the connection between this medication and weight gain. There are several factors that could be contributing to this issue, including:

1. Increased Appetite

One of the most common side effects of antihistamines is an increase in appetite. This could lead to overeating and, ultimately, weight gain in some individuals. If you find that your appetite has increased since starting Cinnarizine, it may be worthwhile to discuss this with your healthcare provider.

2. Sedation and Fatigue

Another common side effect of antihistamines is sedation or drowsiness. This can lead to decreased physical activity and a more sedentary lifestyle, which can contribute to weight gain. If you are experiencing excessive fatigue or drowsiness while taking Cinnarizine, it may be necessary to adjust your daily routine to ensure you are still getting enough physical activity.

3. Fluid Retention

In some cases, Cinnarizine may cause fluid retention, which can lead to weight gain. This is typically a temporary side effect that resolves once the medication is discontinued. If you suspect that you are retaining fluid while taking Cinnarizine, it's important to consult with your healthcare provider for further evaluation and guidance.

Managing Weight Gain While Taking Cinnarizine

If you're concerned about weight gain while taking Cinnarizine, there are several steps you can take to help manage this potential side effect. These include:

1. Monitoring Your Diet

Pay close attention to your caloric intake and make healthy food choices. This can help balance out any potential increase in appetite caused by Cinnarizine. Incorporating more fruits, vegetables, lean proteins, and whole grains into your diet can help you maintain a healthy weight.

2. Staying Active

Despite the potential sedating effects of Cinnarizine, it's important to maintain a regular exercise routine. Aim for at least 30 minutes of moderate-intensity aerobic activity most days of the week. This can help counteract any decreased physical activity that may result from drowsiness or fatigue.

3. Consult Your Healthcare Provider

If you're experiencing significant weight gain while taking Cinnarizine, it's important to discuss this with your healthcare provider. They can help determine if the medication is indeed the cause of your weight gain and may be able to recommend alternative treatments or adjustments to your current regimen.

Alternative Treatment Options

If Cinnarizine is causing weight gain and impacting your overall health, it may be necessary to explore alternative treatment options. There are several other medications available that can help manage the symptoms of vertigo, motion sickness, and Meniere's disease without the potential side effects of weight gain. Some of these alternatives include:

1. Meclizine: Another antihistamine that can be used to treat vertigo and motion sickness. It is less likely to cause weight gain compared to Cinnarizine.

2. Betahistine: A medication that works specifically to reduce the frequency and severity of vertigo attacks in individuals with Meniere's disease. It has not been associated with weight gain.

3. Scopolamine: A medication that can be used to prevent motion sickness and has not been linked to weight gain.

It's important to discuss any potential treatment changes with your healthcare provider, as they can help determine the best course of action based on your individual needs and medical history.


In conclusion, there is a potential connection between Cinnarizine and weight gain, primarily due to the medication's antihistamine properties. However, by monitoring your diet, staying active, and consulting with your healthcare provider, it is possible to manage this side effect and maintain a healthy weight. If necessary, alternative treatment options are available that may be better suited for your individual needs. As always, it's important to communicate any concerns or side effects with your healthcare provider to ensure the best possible care for your specific situation.


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